3-(Trifluoromethoxy)pyridin-2-amine

• CAT Number: L034857
• CAS Number: 1206981-49-8
• Molecular Formula: C6H5F3N2O
• Molecular Weight: 178.11
• Purity: ≥95%
• IUPAC Name: 3-(trifluoromethoxy)pyridin-2-amine
• InChI: InChI=1S/C6H5F3N2O/c7-6(8,9)12-4-2-1-3-11-5(4)10/h1-3H,(H2,10,11)
• InChIKey: WCRYAXUZQGCSAO-UHFFFAOYSA-N
• SMILES: C1=CC(=C(N=C1)N)OC(F)(F)F

3-(Trifluoromethoxy)pyridin-2-amine（Cat No.:L034857）is a heteroaromatic compound featuring a pyridine ring substituted with a trifluoromethoxy group at the 3-position and an amino group at the 2-position. The trifluoromethoxy group imparts strong electron-withdrawing and lipophilic properties, enhancing metabolic stability and membrane permeability, while the amino group offers a reactive site for further derivatization. This combination makes the molecule valuable in pharmaceutical and agrochemical research, particularly in the development of kinase inhibitors, anti-inflammatory agents, and other bioactive compounds. Its unique electronic profile supports diverse synthetic applications in medicinal chemistry.