(3-((tert-Butyldimethylsilyl)oxy)phenyl)boronic acid

• CAT Number: L041706
• CAS Number: 261621-12-9
• Molecular Formula: C12H21BO3Si
• Molecular Weight: 252.19
• Purity: ≥95%
• IUPAC Name: [3-[tert-butyl(dimethyl)silyl]oxyphenyl]boronic acid
• InChI: InChI=1S/C12H21BO3Si/c1-12(2,3)17(4,5)16-11-8-6-7-10(9-11)13(14)15/h6-9,14-15H,1-5H3
• InChIKey: RDQWADDNQONTLB-UHFFFAOYSA-N
• SMILES: B(C1=CC(=CC=C1)O[Si](C)(C)C(C)(C)C)(O)O

(3-((tert-Butyldimethylsilyl)oxy)phenyl)boronic acid（Cat No.:L041706）is a protected boronic acid derivative featuring a tert-butyldimethylsilyl (TBDMS) ether group at the meta-position of the phenyl ring. The boronic acid functionality makes it a key reagent in Suzuki-Miyaura cross-coupling reactions, allowing the formation of C–C bonds in the synthesis of biaryl and heterocyclic compounds. The TBDMS group serves as a robust protecting group for phenols, offering stability under basic and mildly acidic conditions while being easily removable under fluoride-mediated conditions. This compound is widely used in medicinal and material chemistry for building complex molecular architectures.