3-Quinuclidinone Hydrochloride

• CAT Number: R024637
• CAS Number: 1193-65-3
• Molecular Formula: C7H12ClNO
• Molecular Weight: 161.63
• Purity: ≥95%
• Synonyms: 1-Azabicyclo[2.2.2]octan-3-one Hydrochloride;?3-Quinuclidinone Hydrochloride; 3-Oxoquinuclidine Hydrochloride
• Storage: -20°C
• IUPAC Name: 1-azabicyclo[2.2.2]octan-3-one;hydrochloride
• InChI: InChI=1S/C7H11NO.ClH/c9-7-5-8-3-1-6(7)2-4-8;/h6H,1-5H2;1H
• InChIKey: RFDPHKHXPMDJJD-UHFFFAOYSA-N
• SMILES: C1CN2CCC1C(=O)C2.Cl

3-Quinuclidinone hydrochloride(CAT: R024637) is a bicyclic nitrogen-containing compound widely used as a versatile intermediate in pharmaceutical and chemical research. As a crystalline salt form of 3-quinuclidinone, it features a rigid quinuclidine scaffold with a ketone functionality, offering high reactivity in nucleophilic addition and reductive amination reactions. This compound is a key building block in the synthesis of anticholinergic agents, CNS-active compounds, and muscarinic receptor modulators. Its well-defined stereochemistry and structural similarity to biologically active alkaloids make it valuable for structure–activity relationship (SAR) studies. Additionally, it serves as a precursor in the development of complex heterocycles and bioactive small molecules.