3-O-Acetyl-11-hydroxy-beta-boswellic acid

• CAT Number: I044920
• CAS Number: 146019-25-2
• Molecular Formula: C32H50O5
• Molecular Weight: 514.74
• Purity: ≥95%
• Synonyms: (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14R,14aR,14bS)-3-acetyloxy-14-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picene-4-carboxylic acid
• InChI: InChI=1S/C32H50O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,22-26,34H,9-16H2,1-8H3,(H,35,36)/t18-,19+,22-,23-,24-,25+,26-,28-,29+,30-,31-,32-/m1/s1
• InChIKey: GKZSILIAFXNPRA-GHQZQFNUSA-N
• SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=C[C@H]([C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)OC(=O)C)C)C)O)[C@@H]2[C@H]1C)C)C

3-O-Acetyl-11-hydroxy-β-boswellic acid（Cat No.:I044920）is a pentacyclic triterpenoid derived from the resin of Boswellia species, commonly known as frankincense. It is a bioactive derivative of boswellic acid, featuring an acetyl group at the 3-position and a hydroxyl group at the 11-position, enhancing its pharmacological profile. This compound is known for its potent anti-inflammatory and anti-cancer properties, particularly through inhibition of 5-lipoxygenase and modulation of NF-κB signaling. It is under investigation for therapeutic use in chronic inflammatory diseases, including arthritis, colitis, and certain cancers, making it valuable in natural product-based drug development.