3-Iodooxetane

• CAT Number: L013690
• CAS Number: 26272-85-5
• Molecular Formula: C3H5IO
• Molecular Weight: 183.98
• Purity: ≥95%
• IUPAC Name: 3-iodooxetane
• InChI: InChI=1S/C3H5IO/c4-3-1-5-2-3/h3H,1-2H2
• InChIKey: KBEIFKMKVCDETC-UHFFFAOYSA-N
• SMILES: C1C(CO1)I

3-Iodooxetane(CAT: L013690) is a halogenated four-membered cyclic ether featuring an iodine atom at the 3-position of the oxetane ring. This strained, highly reactive compound is a versatile intermediate in synthetic organic chemistry, particularly in the development of pharmaceuticals and agrochemicals. The iodine substituent allows for efficient functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald–Hartwig), enabling the introduction of diverse substituents. Oxetanes are increasingly explored for their ability to improve the physicochemical properties of drug candidates, including metabolic stability and solubility. 3-Iodooxetane is especially valuable in medicinal chemistry for constructing oxygen-containing scaffolds and optimizing drug-like molecular architectures.