3-Hydroxyphthalic anhydride

• CAT Number: L020051
• CAS Number: 37418-88-5
• Molecular Formula: C8H4O4
• Molecular Weight: 164.11
• Purity: ≥95%
• IUPAC Name: 4-hydroxy-2-benzofuran-1,3-dione
• InChI: InChI=1S/C8H4O4/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3,9H
• InChIKey: CCTOEAMRIIXGDJ-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C(=C1)O)C(=O)OC2=O

3-Hydroxyphthalic anhydride(CAT: L020051) is an aromatic anhydride featuring a hydroxyl group ortho to the anhydride moiety, making it a reactive intermediate in the synthesis of dyes, polymers, and pharmaceutical compounds. Its hydroxyl functionality allows for selective derivatization through esterification or etherification, while the anhydride ring readily participates in ring-opening reactions with nucleophiles such as amines and alcohols. This compound is often used in the preparation of polyimides, functionalized pigments, and bioconjugation reagents. In biochemistry, 3-hydroxyphthalic anhydride has been employed to modify proteins and peptides, particularly in the development of enzyme inhibitors and antigen carriers for immunological research and vaccine design.