3-Fluorobenzenesulfonyl Chloride

• CAT Number: R060209
• CAS Number: 701-27-9
• Molecular Formula: C6H4ClFO2S
• Molecular Weight: 194.60
• Purity: ≥95%
• Synonyms: 3-Fluoro-benzenesulfonyl Chloride; m-Fluoro-benzenesulfonyl Chloride; 3-Fluorobenzene-1-sulfonyl Chloride; 3-Fluorophenylsulfonyl Chloride
• Storage: Store at -20C
• IUPAC Name: 3-fluorobenzenesulfonyl chloride
• InChI: InChI=1S/C6H4ClFO2S/c7-11(9,10)6-3-1-2-5(8)4-6/h1-4H
• InChIKey: OKYSUJVCDXZGKE-UHFFFAOYSA-N
• SMILES: C1=CC(=CC(=C1)S(=O)(=O)Cl)F

3-Fluorobenzenesulfonyl chloride(CAT: R060209) is an aromatic sulfonyl chloride featuring a fluorine substituent at the meta position of the benzene ring. It is widely used as a reactive intermediate in the synthesis of sulfonamides, sulfonate esters, and other organosulfur compounds. The presence of the electron-withdrawing fluorine atom enhances the compound’s reactivity and selectivity in electrophilic substitution and coupling reactions. This reagent is especially valuable in pharmaceutical, agrochemical, and materials research, where it contributes to the design of bioactive molecules, fluorinated scaffolds, and functionalized polymers. Its versatility makes it a key building block in advanced synthetic and medicinal chemistry.