For research use only. Not for therapeutic Use.
3-Desacetyl Cefotaxime Lactone(CAT: R052579) is a key metabolite and degradation product of the third-generation cephalosporin Cefotaxime. Formed via enzymatic hydrolysis or chemical instability, it represents an important intermediate in studying β-lactam antibiotic metabolism, resistance mechanisms, and stability profiles. This lactone derivative is frequently used in research to evaluate the role of β-lactamases in antibiotic inactivation, as well as in pharmacokinetic and metabolic pathway studies. By serving as a reference standard, 3-Desacetyl Cefotaxime Lactone aids in bioanalytical assays, drug metabolism investigations, and antimicrobial resistance research, offering insights into cephalosporin activity and microbial defense strategies.
| CAS Number | 66340-33-8 |
| Synonyms | (2Z)-2-(2-amino-1,3-thiazol-4-yl)-N-[(4R,5R)-3,11-dioxo-10-oxa-6-thia-2-azatricyclo[6.3.0.02,5]undec-1(8)-en-4-yl]-2-methoxyiminoacetamide |
| Molecular Formula | C14H13N5O5S2 |
| Purity | ≥95% |
| IUPAC Name | (2Z)-2-(2-amino-1,3-thiazol-4-yl)-N-[(4R,5R)-3,11-dioxo-10-oxa-6-thia-2-azatricyclo[6.3.0.02,5]undec-1(8)-en-4-yl]-2-methoxyiminoacetamide |
| InChI | InChI=1S/C14H13N5O5S2/c1-23-18-7(6-4-26-14(15)16-6)10(20)17-8-11(21)19-9-5(2-24-13(9)22)3-25-12(8)19/h4,8,12H,2-3H2,1H3,(H2,15,16)(H,17,20)/b18-7-/t8-,12-/m1/s1 |
| InChIKey | MCSWUKXFFGUOQE-GHXIOONMSA-N |
| SMILES | CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C4=C(COC4=O)CS3 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
