3'-Deoxyuridine-5'-triphosphate trisodium

For research use only. Not for therapeutic Use.

  • CAT Number: I044513
  • Molecular Formula: C9H12N2Na3O14P3
  • Molecular Weight: 534.09
  • Purity: ≥95%
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3′-Deoxyuridine-5′-triphosphate trisodium(Cat No.:I044513)is a synthetic nucleotide analog of uridine triphosphate (UTP), in which the 3′-hydroxyl group is absent. This modification prevents further elongation once incorporated into a growing nucleic acid chain, effectively terminating DNA or RNA synthesis. As a trisodium salt, it is water-soluble and suitable for enzymatic studies and biochemical assays. It is commonly used in research to study polymerase function, nucleic acid metabolism, and antiviral drug mechanisms. By mimicking natural nucleotides while blocking chain extension, it aids in elucidating replication and transcription dynamics in vitro.


Molecular Formula C9H12N2Na3O14P3
Purity ≥95%
IUPAC Name trisodium;[[[(2S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
InChI InChI=1S/C9H15N2O14P3.3Na/c12-6-3-5(23-8(6)11-2-1-7(13)10-9(11)14)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;;/q;3*+1/p-3/t5-,6+,8+;;;/m0.../s1
InChIKey UYUYUMCIVOBKCF-MILVPLDLSA-K
SMILES C1[C@H](O[C@H]([C@@H]1O)N2C=CC(=O)NC2=O)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-].[Na+].[Na+].[Na+]
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