3-Chloro-5H-pyrrolo[2,3-b]pyrazine

• CAT Number: R049819
• CAS Number: 1111638-10-8
• Molecular Formula: C6H4ClN3
• Molecular Weight: 153.57
• Purity: ≥95%
• Synonyms: 3-Chloro-5H-pyrrolo[2,3-b]pyrazine
• Storage: Store at RT
• IUPAC Name: 3-chloro-5H-pyrrolo[2,3-b]pyrazine
• InChI: InChI=1S/C6H4ClN3/c7-5-3-9-4-1-2-8-6(4)10-5/h1-3H,(H,8,10)
• InChIKey: QWTQGZAUKADLTO-UHFFFAOYSA-N
• SMILES: C1=CNC2=NC(=CN=C21)Cl

3-Chloro-5H-pyrrolo[2,3-b]pyrazine (Cat No.: R049819) is a heterocyclic compound featuring a fused pyrrole and pyrazine ring system with a chlorine substituent at the third position. This compound serves as a valuable building block in medicinal chemistry, particularly in the synthesis of kinase inhibitors and other bioactive molecules. Its structural framework supports hydrogen bonding and π-stacking interactions, making it suitable for drug design. The chlorine atom enhances its reactivity, enabling further functionalization in structure–activity relationship (SAR) studies.