3-Chloro-2-nitropyridine

• CAT Number: L041280
• CAS Number: 54231-32-2
• Molecular Formula: C5H3ClN2O2
• Molecular Weight: 158.54
• Purity: ≥95%
• IUPAC Name: 3-chloro-2-nitropyridine
• InChI: InChI=1S/C5H3ClN2O2/c6-4-2-1-3-7-5(4)8(9)10/h1-3H
• InChIKey: PSGASDJUCYTRAD-UHFFFAOYSA-N
• SMILES: C1=CC(=C(N=C1)[N+](=O)[O-])Cl

3-Chloro-2-nitropyridine(CAT: L041280) is a halogenated nitropyridine derivative featuring a chlorine atom at the 3-position and a nitro group at the 2-position of the pyridine ring. This electron-deficient heterocycle is a valuable intermediate in pharmaceutical, agrochemical, and material synthesis. The compound’s reactivity is enhanced by the nitro group’s electron-withdrawing effect, enabling nucleophilic aromatic substitution (SNAr) and cross-coupling reactions at the chloro position. It is commonly used in the preparation of substituted pyridines, heterocyclic scaffolds, and nitrogen-containing ligands. Its structural features make it especially useful for constructing bioactive molecules and exploring structure–activity relationships in drug discovery and development programs.