3-Bromo-5-nitrobenzotrifluoride

• CAT Number: L048454
• CAS Number: 630125-49-4
• Molecular Formula: C7H3BrF3NO2
• Molecular Weight: 270.11
• Purity: ≥95%
• IUPAC Name: 1-bromo-3-nitro-5-(trifluoromethyl)benzene
• InChI: InChI=1S/C7H3BrF3NO2/c8-5-1-4(7(9,10)11)2-6(3-5)12(13)14/h1-3H
• InChIKey: YHTVYRKVFAFVLP-UHFFFAOYSA-N
• SMILES: C1=C(C=C(C=C1[N+](=O)[O-])Br)C(F)(F)F

3-Bromo-5-nitrobenzotrifluoride(CAT: L048454) is a trifluoromethylated aromatic compound featuring a bromine atom at the 3-position and a nitro group at the 5-position of a benzene ring bearing a trifluoromethyl substituent. This electron-deficient, highly functionalized molecule is a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty materials. The bromine allows for cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig), while the nitro group offers avenues for further transformations such as reduction or nucleophilic substitution. The trifluoromethyl group enhances metabolic stability and lipophilicity, making the compound particularly useful in the design of fluorinated drug candidates and bioactive aromatic scaffolds.