3-Bromo-5-fluoroanisole

• CAT Number: L012686
• CAS Number: 29578-39-0
• Molecular Formula: C7H6BrFO
• Molecular Weight: 205.02
• Purity: ≥95%
• IUPAC Name: 1-bromo-3-fluoro-5-methoxybenzene
• InChI: InChI=1S/C7H6BrFO/c1-10-7-3-5(8)2-6(9)4-7/h2-4H,1H3
• InChIKey: XVNQVSGOIUYOPB-UHFFFAOYSA-N
• SMILES: COC1=CC(=CC(=C1)Br)F

3-Bromo-5-fluoroanisole(CAT: L012686) is a halogenated anisole derivative featuring a bromine atom at the 3-position and a fluorine atom at the 5-position on the aromatic ring, along with a methoxy group. This compound serves as a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its dual halogen substitution enables selective cross-coupling reactions, such as Suzuki, Buchwald–Hartwig, or Heck reactions, offering flexible pathways to functionalized aromatic compounds. The methoxy group modulates electron density and enhances reactivity, making this molecule a useful scaffold in medicinal chemistry for designing bioactive agents and exploring structure–activity relationships in aromatic systems.