3-Azido-L-alanine hydrochloride

• CAT Number: I042512
• CAS Number: 1620171-64-3
• Molecular Formula: C3H7ClN4O2
• Molecular Weight: 166.57
• Purity: ≥95%
• Synonyms: (2S)-2-amino-3-azidopropanoic acid;hydrochloride
• InChI: InChI=1S/C3H6N4O2.ClH/c4-2(3(8)9)1-6-7-5;/h2H,1,4H2,(H,8,9);1H/t2-;/m0./s1
• InChIKey: MQDWRZHPCDDSJZ-DKWTVANSSA-N
• SMILES: C(C(C(=O)O)N)N=[N+]=[N-].Cl

3-Azido-L-alanine hydrochloride (Cat No.: I042512) is an azide-functionalized amino acid derivative, featuring an azido group at the β-position of L-alanine, stabilized as a hydrochloride salt. It is widely used in bioorthogonal chemistry, particularly for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. This compound enables site-specific labeling of peptides and proteins, making it valuable for studying protein function, imaging, and conjugation applications. Its compatibility with cellular systems and incorporation into biomolecules makes it a powerful tool in chemical biology, proteomics, and drug development research.

Reference

[1]. Moschny J, et al. Precursor-Directed Biosynthesis and Fluorescence Labeling of Clickable Microcystins. J Nat Prod. 2020 Jun 26;83(6):1960-1970.
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