3-Aminopropionitrile

• CAT Number: R025391
• CAS Number: 151-18-8
• Molecular Formula: C3H6N2
• Molecular Weight: 70.095
• Purity: ≥95%
• Synonyms: 3-Amino-propionitrile; β-Amino-propionitrile; 1-Cyano-2-aminoethane; 2-Cyanoethylamine; 3-Aminopropanenitrile; Aminopropionitrile; BAPN; N-(2-Cyanoethyl)amine; NSC 40641; β-Alaninenitrile; β-Aminopropionitrile; β-Cyanoethylamine
• Storage: -20°C
• IUPAC Name: 3-aminopropanenitrile
• InChI: InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2
• InChIKey: AGSPXMVUFBBBMO-UHFFFAOYSA-N
• SMILES: C(CN)C#N

3-Aminopropionitrile (CAS 151-18-8), also known as β-Aminopropionitrile, is a specific and irreversible lysyl oxidase(LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes.

Reference

1.Miana, María, et al. "The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats." Disease models & mechanisms 8.6 (2015): 543-551.
2.Yang, Xiaoxiao, et al. "Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells." Oncology reports 29.2 (2013): 541-548.