3-Amino-6-chloropyridine

• CAT Number: R018250
• CAS Number: 5350-93-6
• Molecular Formula: C5H5ClN2
• Molecular Weight: 128.56
• Purity: ≥95%
• Synonyms: 6-Chloro-3-pyridinamine; 5-amino-2-chloropyridine; 2-Chloro-5-aminopyridine; 2-Chloropyridin-5-amine; 6-Chloro-3-aminopyridine; 6-Chloro-3-pyridinamine; 6-Chloropyridin-3-ylamine; NSC 81
• Storage: -20°C
• IUPAC Name: 6-chloropyridin-3-amine
• InChI: InChI=1S/C5H5ClN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H2
• InChIKey: QAJYCQZQLVENRZ-UHFFFAOYSA-N
• SMILES: C1=CC(=NC=C1N)Cl

3-Amino-6-chloropyridine(CAT: R018250) is a halogenated aminopyridine compound featuring an amino group at the 3-position and a chlorine atom at the 6-position on the pyridine ring. This bifunctional heterocycle is a valuable intermediate in pharmaceutical, agrochemical, and material science applications. Its structure allows for selective derivatization through nucleophilic aromatic substitution, cross-coupling, or acylation reactions, enabling the synthesis of complex heterocyclic scaffolds. It is commonly used in the development of kinase inhibitors, antimicrobial agents, and CNS-active compounds. The electron-rich amino group and electron-withdrawing chlorine provide a useful balance for reactivity and functional group compatibility in modern medicinal chemistry.