For research use only. Not for therapeutic Use.
3′-Amino-3′-deoxyadenosine (Cat No.: I045444) is a modified nucleoside in which the 3′-hydroxyl group of adenosine is replaced with an amino group, altering its chemical reactivity and biological properties. This structural change can interfere with nucleic acid synthesis, making it useful as an inhibitor or probe in enzymology and antiviral research. The amino substitution enables selective chemical conjugation for labeling or functionalization. It is applied in studies of nucleoside metabolism, RNA/DNA synthesis, and as a building block in the design of therapeutic nucleoside analogs.
| CAS Number | 2504-55-4 |
| Synonyms | (2R,3R,4S,5S)-4-amino-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol |
| Molecular Formula | C10H14N6O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C10H14N6O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1,11H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1 |
| InChIKey | ILDPUOKUEKVHIL-QYYRPYCUSA-N |
| SMILES | C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)N)O)N |
| Reference | [1]. Gerber, Nancy Nichols, et al. 3′-Amino-3′-deoxyadenosine, an antitumor agent from Helminthosporium. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
