3α,12β-Dihydroxycholanoic Acid

• CAT Number: R027868
• CAS Number: 570-62-7
• Molecular Formula: C24H40O4
• Molecular Weight: 392.58
• Purity: ≥95%
• Synonyms: 3α,12β-Dihydroxy-5β-cholan-24-oic Acid; 3α,12β-Dihydroxy-5β-cholanic Acid; 12-Epideoxycholic Acid; 12-epi-Deoxycholic Acid; 3α,12β-Dihydroxy-5β-cholan-24-oic Acid; 3α,12β-Dihydroxy-5β-cholanic Acid; 3α,12β-Dihydroxy-5β-cholanoic Acid; (R)-4-((3R,5R,
• Storage: -20°C
• IUPAC Name: (4R)-4-[(3R,5R,8R,9S,10S,12R,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• InChI: InChI=1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21-,23+,24-/m1/s1
• InChIKey: KXGVEGMKQFWNSR-MFSKYVBHSA-N
• SMILES: CC(CCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C

3α,12β-Dihydroxycholanoic acid(CAT: R027868) is a synthetic bile acid derivative featuring hydroxyl groups at the 3α and 12β positions on the cholane framework. This specific hydroxylation pattern alters its physicochemical and biological properties, making it a valuable compound for studying bile acid function, micelle formation, and lipid absorption. It is commonly used in research on bile acid transport, enterohepatic circulation, and liver function. Its structural similarity to natural bile acids allows it to act as a probe for receptor interactions, such as FXR and TGR5 signaling pathways.