25(R,S)-Ruscogenin

• CAT Number: I044930
• CAS Number: 874485-32-2
• Molecular Formula: C27H42O4
• Molecular Weight: 430.62
• Purity: ≥95%
• Synonyms: (1S,2S,4S,6R,7S,8R,9S,12S,13R,14R,16R)-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2′-oxane]-14,16-diol
• IUPAC Name: (1S,2S,4S,6R,7S,8R,9S,12S,13R,14R,16R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-14,16-diol
• InChI: InChI=1S/C27H42O4/c1-15-7-10-27(30-14-15)16(2)24-22(31-27)13-21-19-6-5-17-11-18(28)12-23(29)26(17,4)20(19)8-9-25(21,24)3/h5,15-16,18-24,28-29H,6-14H2,1-4H3/t15?,16-,18+,19+,20-,21-,22-,23+,24-,25-,26-,27+/m0/s1
• InChIKey: QMQIQBOGXYYATH-ZBTLHKOBSA-N
• SMILES: C[C@H]1[C@H]2[C@H](C[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4([C@@H](C[C@@H](C5)O)O)C)C)O[C@]16CCC(CO6)C

25(R,S)-Ruscogenin（Cat No.:I044930）is a steroidal sapogenin found in plants of the Ruscus and Ophiopogon genera, used traditionally in Chinese and European herbal medicine. As a mixture of the 25(R) and 25(S) stereoisomers, it exhibits notable pharmacological effects, including anti-inflammatory, vascular-protective, and neuroprotective activities. 25(R,S)-Ruscogenin is known to strengthen capillary walls, reduce vascular permeability, and modulate inflammatory signaling pathways such as NF-κB. It is under investigation for its potential in treating chronic inflammatory diseases, neurodegeneration, and circulatory disorders, making it a valuable compound in both natural product research and therapeutic development.