25B-<wbr></wbr>NBF is an <em>N</em>-<wbr></wbr>fluorobenzyl derivative of the phenethylamine hallucinogen 2C-<wbr></wbr>B (Item No. <span class=/itemid/>11734</span>), which acts as a highly potent agonist for the 5-<wbr></wbr>HT<sub>2C</sub> receptor. 25B-<wbr></wbr>NBF binds human 5-<wbr></wbr>HT<sub>2A</sub> receptors and rat 5-<wbr></wbr>HT<sub>2C</sub> receptors with pK<sub>i</sub> values of 8.57 and 7.73, respectively. This product is intended for forensic and research applications.
| Catalog Number | R065148 |
| CAS Number | 1539266-17-5 |
| Synonyms | 2C-B-NBF |
| Molecular Formula | C17H20BrClFNO2 |
| Purity | 95% |
| Storage | -20°C |
| IUPAC Name | 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-fluorophenyl)methyl]ethanamine;hydrochloride |
| InChI | InChI=1S/C17H19BrFNO2.ClH/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-20-11-13-5-3-4-6-15(13)19;/h3-6,9-10,20H,7-8,11H2,1-2H3;1H |
| InChIKey | OSPTXOUFWUFHAM-UHFFFAOYSA-N |
| SMILES | COC1=CC(=C(C=C1CCNCC2=CC=CC=C2F)OC)Br.Cl |
| Reference | 1.Hansen, M.,Phonekeo, K.,Paine, J.S., et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS Chem.Neurosci. 5(3), 243-249 (2014). |
