2,4,6-Trifluorophenylacetic acid

• CAT Number: L019906
• CAS Number: 209991-63-9
• Molecular Formula: C8H5F3O2
• Molecular Weight: 190.12
• Purity: ≥95%
• IUPAC Name: 2-(2,4,6-trifluorophenyl)acetic acid
• InChI: InChI=1S/C8H5F3O2/c9-4-1-6(10)5(3-8(12)13)7(11)2-4/h1-2H,3H2,(H,12,13)
• InChIKey: NGEKZFHYZPHNKQ-UHFFFAOYSA-N
• SMILES: C1=C(C=C(C(=C1F)CC(=O)O)F)F

2,4,6-Trifluorophenylacetic acid（Cat No.:L019906）is an aromatic carboxylic acid featuring a phenyl ring substituted with fluorine atoms at the 2, 4, and 6 positions and a methylene-linked carboxylic acid group. The trifluorination enhances the compound’s electron-withdrawing character, increasing acidity and affecting reactivity in electrophilic and nucleophilic aromatic substitutions. It serves as a valuable intermediate in pharmaceutical, agrochemical, and fluorinated material synthesis. The carboxylic acid group enables transformations such as amidation, esterification, or coupling reactions. Its unique electronic properties make it useful in designing bioactive molecules with improved metabolic stability and binding affinity.