2,4,5-Trifluorobenzeneacetic Acid

• CAT Number: R019798
• CAS Number: 209995-38-0
• Molecular Formula: C8H5F3O2
• Molecular Weight: 190.12
• Purity: ≥95%
• Synonyms: (2,4,5-Trifluorophenyl)acetic Acid
• Storage: -20°C
• IUPAC Name: 2-(2,4,5-trifluorophenyl)acetic acid
• InChI: InChI=1S/C8H5F3O2/c9-5-3-7(11)6(10)1-4(5)2-8(12)13/h1,3H,2H2,(H,12,13)
• InChIKey: YSQLGGQUQDTBSL-UHFFFAOYSA-N
• SMILES: C1=C(C(=CC(=C1F)F)F)CC(=O)O

2,4,5-Trifluorobenzeneacetic acid(CAT: R019798) is an aromatic carboxylic acid featuring three strategically positioned fluorine atoms on the benzene ring, along with an acetic acid side chain. This fluorinated building block is valuable in the synthesis of pharmaceutical intermediates, agrochemicals, and functional materials, offering enhanced metabolic stability, lipophilicity, and electron-withdrawing effects. Its unique substitution pattern allows for regioselective derivatization and supports diverse applications in medicinal chemistry and fluorinated analog development. The presence of multiple fluorine atoms contributes to improved binding affinity and bioavailability in drug candidates, making this compound a key component in modern structure–activity relationship (SAR) studies.