2,3,6,7-Tetrahydro-8-hydroxy-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde

• CAT Number: L047396
• CAS Number: 63149-33-7
• Molecular Formula: C13H15NO2
• Molecular Weight: 217.26
• Purity: ≥95%
• IUPAC Name: 6-hydroxy-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene-7-carbaldehyde
• InChI: InChI=1S/C13H15NO2/c15-8-10-7-9-3-1-5-14-6-2-4-11(12(9)14)13(10)16/h7-8,16H,1-6H2
• InChIKey: NRZXBDYODHLZBF-UHFFFAOYSA-N
• SMILES: C1CC2=CC(=C(C3=C2N(C1)CCC3)O)C=O

2,3,6,7-Tetrahydro-8-hydroxy-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde(CAT: L047396) is a polycyclic nitrogen-containing heterocycle featuring a quinolizine core with partial saturation, a hydroxy group at the 8-position, and a formyl group at the 9-position. Its fused-ring structure offers rigidity and three-dimensionality, making it a valuable scaffold in medicinal chemistry for the development of CNS-active compounds, particularly those targeting dopaminergic or serotonergic pathways. The aldehyde group provides a handle for further derivatization through reductive amination or condensation reactions. This compound is suitable for use in structure–activity relationship (SAR) studies, natural product synthesis, and the development of bioactive alkaloid analogs and neuropharmacological agents.