2,3-Pyridinedicarboxylic Acid

• CAT Number: R006831
• CAS Number: 89-00-9
• Molecular Formula: C7H5NO4
• Molecular Weight: 167.12
• Purity: ≥95%
• Synonyms: Quinolinic Acid; Pyridine-2,3-dicarboxylic Acid; Pyridin-2,3-dicarbonsaeure; NSC 13127; NSC 18836; NSC 403247
• Target: Neuronal Signaling
• Solubility: >7.8mg/mL in DMSO
• Storage: Store at RT
• IUPAC Name: pyridine-2,3-dicarboxylic acid
• InChI: InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)
• InChIKey: GJAWHXHKYYXBSV-UHFFFAOYSA-N
• SMILES: C1=CC(=C(N=C1)C(=O)O)C(=O)O

2,3-Pyridinedicarboxylic acid（Cat No.:R006831）, also known as quinolinic acid, is a heteroaromatic dicarboxylic acid featuring two carboxyl groups at the 2 and 3 positions of a pyridine ring. It is a naturally occurring metabolite in the kynurenine pathway of tryptophan degradation and is known for its neuroactive properties, particularly as an NMDA receptor agonist. In biomedical research, it is studied for its role in neurodegenerative diseases and inflammation. The compound is also used as a chelating agent and building block in coordination chemistry. It is typically supplied as a crystalline solid, soluble in water.