2’,3’-Di-O-acetyl-5’-deoxy-5-fluorocytidine

• CAT Number: R003931
• CAS Number: 161599-46-8
• Molecular Formula: C13H16FN3O6
• Molecular Weight: 329.28
• Purity: ≥95%
• Synonyms: 5’-Deoxy-5-fluoro-cytidine 2’,3’-Diacetate
• Storage: Store at RT
• IUPAC Name: [(2R,3R,4R,5R)-4-acetyloxy-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-2-methyloxolan-3-yl] acetate
• InChI: InChI=1S/C13H16FN3O6/c1-5-9(22-6(2)18)10(23-7(3)19)12(21-5)17-4-8(14)11(15)16-13(17)20/h4-5,9-10,12H,1-3H3,(H2,15,16,20)/t5-,9-,10-,12-/m1/s1
• InChIKey: NWJBWNIUGNXJGO-RPULLILYSA-N
• SMILES: C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=NC2=O)N)F)OC(=O)C)OC(=O)C

2’,3’-Di-O-acetyl-5’-deoxy-5-fluorocytidine（Cat No.:R003931）is a chemically modified nucleoside analog derived from 5-fluorocytidine, in which the 2’- and 3’-hydroxyl groups are acetylated and the 5’-hydroxyl is deoxygenated. This compound is often used as an intermediate in the synthesis of fluoropyrimidine-based anticancer agents such as capecitabine or 5-fluorouracil derivatives. The acetyl groups protect the sugar moiety during synthetic steps, while the 5-fluoro modification enhances antitumor activity by interfering with DNA and RNA synthesis. It is typically supplied as a white to off-white solid, soluble in organic solvents.