2,2,2-Trifluoroethylamine Hydrochloride

• CAT Number: R022902
• CAS Number: 373-88-6
• Molecular Formula: C2H5ClF3N
• Molecular Weight: 135.51
• Purity: ≥95%
• Synonyms: 2,2,2-Trifluoroethylamine Hydrochloride; 2,2,2-Trifluoro-1-ethanamine Hydrochloride; 2,2,2-Trifluoroethanamine Hydrochloride; 2,2,2-Trifluoroethylamine Hydrochloride
• Storage: -20°C
• IUPAC Name: 2,2,2-trifluoroethanamine;hydrochloride
• InChI: InChI=1S/C2H4F3N.ClH/c3-2(4,5)1-6;/h1,6H2;1H
• InChIKey: ZTUJDPKOHPKRMO-UHFFFAOYSA-N
• SMILES: C(C(F)(F)F)N.Cl

2,2,2-Trifluoroethylamine hydrochloride（Cat No.:R022902）is a fluorinated amine salt featuring a trifluoromethyl group (-CF₃) bonded to an ethylamine backbone, stabilized as a hydrochloride for enhanced solubility and shelf life. This compound is widely used in medicinal and agrochemical synthesis due to the strong electron-withdrawing effect of the CF₃ group, which can modulate biological activity and metabolic stability. It serves as a valuable building block for introducing fluorine into drug candidates, often improving bioavailability, membrane permeability, and resistance to enzymatic degradation. Its reactivity makes it ideal for coupling and derivatization reactions.