2,2-Difluorobenzodioxole-4-carboxaldehyde

• CAT Number: M026140
• CAS Number: 119895-68-0
• Molecular Formula: C8H4F2O3
• Molecular Weight: 186.11
• Purity: ≥95%
• Storage: Desiccate at -20C
• IUPAC Name: 2,2-difluoro-1,3-benzodioxole-4-carbaldehyde
• InChI: InChI=1S/C8H4F2O3/c9-8(10)12-6-3-1-2-5(4-11)7(6)13-8/h1-4H
• InChIKey: NIBFJPXGNVPNHK-UHFFFAOYSA-N
• SMILES: C1=CC(=C2C(=C1)OC(O2)(F)F)C=O

2,2-Difluorobenzodioxole-4-carboxaldehyde (Cat No.: M026140) is an aromatic compound featuring a benzodioxole ring substituted with two fluorine atoms at the 2-position and a formyl group at the 4-position. The presence of fluorine enhances its electrophilicity, metabolic stability, and lipophilicity, making it a valuable intermediate in medicinal and agrochemical synthesis. It is often employed in the design of bioactive molecules, including enzyme inhibitors and pharmaceutical candidates, where the difluoromethylene group serves as a bioisostere for oxygen or hydroxyl functionalities.