2,2-Difluorobenzo[d][1,3]dioxole-5-carbaldehyde

• CAT Number: L020153
• CAS Number: 656-42-8
• Molecular Formula: C8H4F2O3
• Molecular Weight: 186.11
• Purity: ≥95%
• IUPAC Name: 2,2-difluoro-1,3-benzodioxole-5-carbaldehyde
• InChI: InChI=1S/C8H4F2O3/c9-8(10)12-6-2-1-5(4-11)3-7(6)13-8/h1-4H
• InChIKey: GGERGLKEDUUSAP-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C=C1C=O)OC(O2)(F)F

2,2-Difluorobenzo[d][1,3]dioxole-5-carbaldehyde（Cat No.:L020153）is a fluorinated aromatic aldehyde featuring a benzodioxole core with two fluorine atoms at the 2-position and an aldehyde group at the 5-position. This compound is valued in medicinal and agrochemical research for its electron-deficient, rigid scaffold, which enhances bioactivity and metabolic stability in target molecules. The difluoromethylene group contributes to increased lipophilicity and resistance to enzymatic degradation, while the aldehyde group serves as a versatile handle for further functionalization. It is commonly used in the synthesis of heterocycles, fluorinated intermediates, and bioactive compounds.