21-Methoxy Triamcinolone Acetonide (Cat No.:C001122) is a modified derivative of triamcinolone acetonide, a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. The addition of a methoxy group at the 21st position alters the compound’s structure, potentially affecting its pharmacological activities. This modified version may be of interest in pharmaceutical research to investigate the impact of structural modifications on corticosteroid activity.
| Catalog Number | C001122 |
| CAS Number | 161740-70-1 |
| Synonyms | (11β,16α)- 9-Fluoro-11,21-dihydroxy-21-methoxy-16,17-[(1-methylethylidene)bis(oxy)]Pregna-1,4-diene-3,20-dione |
| Molecular Formula | C₂₅H₃₃FO₇ |
| Purity | ≥95% |
| Solubility | Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly, Heated) |
| Appearance | Off-White to Pale Yellow Solid |
| Storage | -20°C, Hygroscopic |
| IUPAC Name | (1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-8-(2-hydroxy-2-methoxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one |
| InChI | 1S/C25H33FO7/c1-21(2)32-18-11-16-15-7-6-13-10-14(27)8-9-22(13,3)24(15,26)17(28)12-23(16,4)25(18,33-21)19(29)20(30)31-5/h8-10,15-18,20,28,30H,6-7,11-12H2,1-5H3/t15-,16-,17-,18+,20?,22-,23-,24-,25-/m0/s1 |
| InChIKey | PWLCESSADNLVMG-VKADFKIWSA-N |
| SMILES | C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)C(O)OC)CCC5=CC(=O)C=C[C@@]53C)F)O |
