For research use only. Not for therapeutic Use.
21-Deoxycortisol-d8（Cat No.:I044127）is a deuterated form of 21-deoxycortisol, labeled with eight deuterium atoms, primarily used as an internal standard in mass spectrometry and pharmacokinetic studies. This stable isotope-labeled compound enables accurate quantification of endogenous 21-deoxycortisol levels in biological samples, aiding in the diagnosis and monitoring of congenital adrenal hyperplasia (CAH) and other adrenal disorders. Its chemical stability and isotopic distinction make it ideal for use in LC-MS/MS assays. 21-Deoxycortisol-d8 supports clinical research and diagnostic development by ensuring precision in steroid hormone profiling and metabolic analysis.
| CAS Number | 2479914-04-8 |
| Synonyms | (8S,9S,10R,11S,13S,14S,17R)-2,2,4,6,6-pentadeuterio-11,17-dihydroxy-10,13-dimethyl-17-(2,2,2-trideuterioacetyl)-7,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one |
| Molecular Formula | C21H22D8O4 |
| Purity | ≥95% |
| IUPAC Name | (8S,9S,10R,11S,13S,14S,17R)-2,2,4,6,6-pentadeuterio-11,17-dihydroxy-10,13-dimethyl-17-(2,2,2-trideuterioacetyl)-7,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one |
| InChI | InChI=1S/C21H30O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3/t15-,16-,17-,18+,19-,20-,21-/m0/s1/i1D3,4D2,6D2,10D |
| InChIKey | LCZBQMKVFQNSJR-ZERYXUNYSA-N |
| SMILES | [2H]C1=C2[C@](CC(C1=O)([2H])[2H])([C@H]3[C@H](C[C@]4([C@H]([C@@H]3CC2([2H])[2H])CC[C@@]4(C(=O)C([2H])([2H])[2H])O)C)O)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
