20(S)-Hydroxy Prednisolone

• CAT Number: R048033
• CAS Number: 2299-46-9
• Molecular Formula: C21H30O5
• Molecular Weight: 362.47
• Purity: ≥95%
• Synonyms: 20(S)-Dihydroprednisolone; 11β,17,20(S),21-Tetrahydroxy-pregna-1,4-dien-3-one; (11β,20S)-11,17,20,21-Tetrahydroxy-pregna-1,4-dien-3-one
• Storage: -20°C
• IUPAC Name: (8S,9S,10R,11S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
• InChI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-18,22,24-26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,17-,18+,19-,20-,21-/m0/s1
• InChIKey: LCOVYWIXMAJCDS-FJWDNACWSA-N
• SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2([C@H](CO)O)O)CCC4=CC(=O)C=C[C@]34C)O

20(S)-Hydroxy prednisolone（Cat No.:R048033）is a stereospecific metabolite of the corticosteroid prednisolone, characterized by the addition of a hydroxyl group at the 20(S) position. This structural modification can influence its biological activity, receptor binding, and metabolic stability. As a glucocorticoid derivative, it retains anti-inflammatory and immunosuppressive properties, though its potency and pharmacokinetics may differ from the parent compound. It is of interest in drug metabolism studies to understand the biotransformation pathways of corticosteroids in the liver. This compound is also used in analytical and pharmacological research to assess steroid activity and metabolite profiling.