2-(Trimethylsilyl)phenyl trifluoromethanesulfonate

For research use only. Not for therapeutic Use.

  • CAT Number: L013614
  • CAS Number: 88284-48-4
  • Molecular Formula: C10H13F3O3SSi
  • Molecular Weight: 298.36
  • Purity: ≥95%
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2-(Trimethylsilyl)phenyl trifluoromethanesulfonate(Cat No.:L013614)is a highly reactive organosilicon compound widely used in cross-coupling and transition-metal-catalyzed reactions. It features a trimethylsilyl group at the ortho-position of a phenyl ring and a trifluoromethanesulfonate (triflate) leaving group, enabling efficient generation of arynes under fluoride activation. This compound is a key precursor in aryne chemistry, facilitating the construction of complex aromatic systems in pharmaceutical, agrochemical, and materials research. Its high reactivity and compatibility with mild conditions make it valuable for synthesizing polycyclic scaffolds, heterocycles, and functionalized aromatic compounds in synthetic organic chemistry.


CAS Number 88284-48-4
Molecular Formula C10H13F3O3SSi
Purity ≥95%
IUPAC Name (2-trimethylsilylphenyl) trifluoromethanesulfonate
InChI InChI=1S/C10H13F3O3SSi/c1-18(2,3)9-7-5-4-6-8(9)16-17(14,15)10(11,12)13/h4-7H,1-3H3
InChIKey XBHPFCIWRHJDCP-UHFFFAOYSA-N
SMILES C[Si](C)(C)C1=CC=CC=C1OS(=O)(=O)C(F)(F)F
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