2-Trifluoromethylphenylboronic acid

For research use only. Not for therapeutic Use.

  • CAT Number: M049373
  • CAS Number: 1423-27-4
  • Molecular Formula: C7H6BF3O2
  • Molecular Weight: 189.93
  • Purity: ≥95%
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2-(Trifluoromethyl)phenylboronic acid(Cat No.:M049373)is an aromatic boronic acid featuring a trifluoromethyl group at the ortho (2-) position of the phenyl ring. The presence of the electron-withdrawing CF₃ group enhances the compound’s stability and modulates its electronic properties, making it a valuable reagent in organic synthesis. It is commonly used in Suzuki–Miyaura cross-coupling reactions for forming C–C bonds, especially in the development of pharmaceuticals, agrochemicals, and advanced materials. The boronic acid functionality allows versatile reactivity, while the trifluoromethyl group contributes to metabolic stability and improved bioactivity in target molecules.


CAS Number 1423-27-4
Molecular Formula C7H6BF3O2
Purity ≥95%
Storage -20°C
IUPAC Name [2-(trifluoromethyl)phenyl]boronic acid
InChI InChI=1S/C7H6BF3O2/c9-7(10,11)5-3-1-2-4-6(5)8(12)13/h1-4,12-13H
InChIKey JNSBEPKGFVENFS-UHFFFAOYSA-N
SMILES B(C1=CC=CC=C1C(F)(F)F)(O)O
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