2-(Trifluoromethoxy)aniline

• CAT Number: R026809
• CAS Number: 1535-75-7
• Molecular Formula: C7H6F3NO
• Molecular Weight: 177.13
• Purity: ≥95%
• Synonyms: α,α,α-Trifluoro-o-anisidine; 2-(Trifluoromethoxy)benzenamine; 2-Trifluoromethoxyaniline; 2-Trifluoromethoxyphenylamine; o-(Trifluoromethoxy)aniline; o-(Trifluoromethoxy)phenylamine
• Storage: Desiccate at +4C
• IUPAC Name: 2-(trifluoromethoxy)aniline
• InChI: InChI=1S/C7H6F3NO/c8-7(9,10)12-6-4-2-1-3-5(6)11/h1-4H,11H2
• InChIKey: ZFCOUBUSGHLCDT-UHFFFAOYSA-N
• SMILES: C1=CC=C(C(=C1)N)OC(F)(F)F

2-(Trifluoromethoxy)aniline（Cat No.:R026809）is an aromatic organic compound featuring an aniline core substituted at the ortho position with a trifluoromethoxy (-OCF₃) group. This electron-withdrawing group enhances the compound’s chemical stability and alters its reactivity, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The compound is often utilized in the development of fluorinated drugs and fine chemicals due to its unique electronic and lipophilic properties. Its structural features contribute to improved bioavailability, metabolic resistance, and receptor binding in medicinal chemistry applications. Safety handling is essential due to its reactive amine functionality.