For research use only. Not for therapeutic Use.
2-Thenoyltrifluoroacetone (TTFA) is an inhibitor of respiration in animals and bacteria. In animals, TTFA binds at the quinone reduction site of succinate:ubiquinone oxidoreductase (SQR; Complex II), preventing ubiquinone from binding. It inhibits NADH fumarate reductase in bacteria. TTFA also inhibits photosystem II in plants and NADH-ubiquinone oxidoreductase of the virus <em>Vibrio cholerae</em>, decreasing cholera toxin production. This compound is also a chelator of metals, including lanthanum, zirconium, hafnium, and neodymium.
| CAS Number | 326-91-0 |
| Synonyms | 1,1,1-Trifluoro-3-(2-thenoyl)acetone; 1,1,1-Trifluoro-4-(2-thienyl)-2,4-butanedione;1-(2-Thienyl)-4,4,4-trifluoro-1,3-butanedione; 1-(2-Thienyl)-4,4,4-trifluorobutane-1,3-dione; 1-Thenoyl-3,3,3-trifluoroacetone?2-(4,4,4-Trifluoroacetoacetyl)thiophene |
| Molecular Formula | C8H5F3O2S |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 4,4,4-trifluoro-1-thiophen-2-ylbutane-1,3-dione |
| InChI | InChI=1S/C8H5F3O2S/c9-8(10,11)7(13)4-5(12)6-2-1-3-14-6/h1-3H,4H2 |
| InChIKey | TXBBUSUXYMIVOS-UHFFFAOYSA-N |
| SMILES | C1=CSC(=C1)C(=O)CC(=O)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
