2-Naphthylamine

• CAT Number: R005004
• CAS Number: 91-59-8
• Molecular Formula: C10H9N
• Molecular Weight: 143.19
• Purity: ≥95%
• Synonyms: 2-Aminonaphthalene; β-Naphthylamine; 2-Naphthalenamine
• Storage: 4°C
• IUPAC Name: naphthalen-2-amine
• InChI: InChI=1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2
• InChIKey: JBIJLHTVPXGSAM-UHFFFAOYSA-N
• SMILES: C1=CC=C2C=C(C=CC2=C1)N

2-Naphthylamine (Cat No.: R005004) is an aromatic amine derived from naphthalene, with the amino group positioned at the 2-position. It appears as a crystalline solid and is used primarily as an intermediate in the synthesis of dyes, pigments, and rubber processing chemicals. Historically significant in the dye industry, 2-naphthylamine is also known for its toxicological properties, particularly its classification as a human carcinogen linked to bladder cancer. Due to its health risks, its industrial use is highly regulated or restricted in many countries.

Reference

1.Gerald Booth "Naphthalene Derivatives" in Ullmann's Encyclopedia of Industrial Chemistry, 2005, Wiley-VCH, Weinheim.
2.Boyland, E., C. E. Dukes, and P. L. Grover. "Carcinogenicity of 2-naphthylhydroxylamine and 2-naphthylamine." British journal of cancer 17.1 (1963): 79.
3.Bonser, Georgiana M., et al. "The carcinogenic activity of 2-naphthylamine." British journal of cancer 10.3 (1956): 533.