2-methylpropane-1-sulfonyl Chloride

• CAT Number: L011381
• CAS Number: 35432-36-1
• Molecular Formula: C4H9ClO2S
• Molecular Weight: 156.63
• Purity: ≥95%
• IUPAC Name: 2-methylpropane-1-sulfonyl chloride
• InChI: InChI=1S/C4H9ClO2S/c1-4(2)3-8(5,6)7/h4H,3H2,1-2H3
• InChIKey: NQLNHTOCFWUYQE-UHFFFAOYSA-N
• SMILES: CC(C)CS(=O)(=O)Cl

2-Methylpropane-1-sulfonyl chloride(CAT: L011381), also known as isobutanesulfonyl chloride, is an aliphatic sulfonyl chloride reagent featuring a branched isobutyl group. It serves as an efficient sulfonylating agent used in organic synthesis to introduce the sulfonyl functional group onto alcohols, amines, and other nucleophiles, forming sulfonates and sulfonamides. This compound is particularly valuable in the preparation of protecting groups, pharmaceutical intermediates, and agrochemical derivatives. Its reactivity and steric profile allow for selective modification of complex molecules. Commonly employed under mild conditions, 2-methylpropane-1-sulfonyl chloride is a useful tool in synthetic and medicinal chemistry for generating sulfonylated structures with improved stability and bioactivity.