2-Methoxyestradiol-d5

• CAT Number: I043930
• CAS Number: 358731-34-7
• Molecular Formula: C19H21D5O3
• Molecular Weight: 307.44
• Purity: ≥95%
• Synonyms: (8R,9S,13S,14S,17S)-1,4,16,16,17-pentadeuterio-2-methoxy-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthrene-3,17-diol
• InChI: InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1/i6D2,9D,10D,18D
• InChIKey: CQOQDQWUFQDJMK-AGCGVRMISA-N
• SMILES: [2H]C1=C2CC[C@@H]3[C@@H](C2=C(C(=C1O)OC)[2H])CC[C@]4([C@H]3CC([C@]4([2H])O)([2H])[2H])C

2-Methoxyestradiol-d5（Cat No.:I043930）is a deuterated analog of 2-methoxyestradiol, a naturally occurring estrogen metabolite with anti-cancer and anti-inflammatory properties. In this compound, five hydrogen atoms are replaced by deuterium isotopes, enhancing its stability and enabling more precise tracking in metabolic studies. 2-Methoxyestradiol-d5 is used in research to investigate the pharmacokinetics, metabolism, and biological activity of estrogen-related compounds. It has potential therapeutic applications, particularly in the treatment of hormone-dependent cancers, and serves as a valuable tool in studying estrogen receptor signaling pathways and the effects of estradiol metabolites in various biological systems.