2-Ketoglutaric Acid

• CAT Number: R015892
• CAS Number: 328-50-7
• Molecular Formula: C5H6O5
• Molecular Weight: 146.10
• Purity: ≥95%
• Synonyms: 2-Oxopentanedioic Acid; 2-Oxo-1,5-pentanedioic Acid; 2-Oxoglutaric Acid; 2-Oxopentanedioic Acid; NSC 17391; α-Ketoglutaric Acid; α-Oxoglutaric Acid; α-Oxopentanedioic Acid; α-keto-Glutaric Acid
• Target: Tyrosinase
• Storage: Store at +4C
• IUPAC Name: 2-oxopentanedioic acid
• InChI: InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
• InChIKey: KPGXRSRHYNQIFN-UHFFFAOYSA-N
• SMILES: C(CC(=O)O)C(=O)C(=O)O

2-Ketoglutaric acid (Cat No.: R015892), also known as alpha-ketoglutaric acid (α-KG), is a key intermediate in the Krebs (citric acid) cycle, playing a vital role in cellular energy metabolism. It is a five-carbon dicarboxylic acid with a ketone group at the 2-position. α-KG participates in amino acid synthesis and nitrogen metabolism by acting as a precursor or acceptor in transamination reactions. It also functions as a cofactor in various enzymatic processes and is studied for its roles in aging, exercise physiology, and metabolic health.