For research use only. Not for therapeutic Use.
2-Iminobiotin hydrobromide(CAT: R015086) is a biotin analog that binds with high affinity to avidin and streptavidin under neutral to alkaline conditions, while releasing under acidic conditions. This reversible binding property makes it a powerful tool for affinity purification, biomolecule labeling, and controlled capture–release strategies. In biological research, it is frequently employed in reversible protein immobilization, biosensor design, and diagnostic assay development. The hydrobromide salt form enhances solubility and handling. 2-Iminobiotin hydrobromide is especially useful in applications requiring non-permanent biotin–avidin interactions, enabling gentle recovery of functional biomolecules for downstream analysis in biochemical and biomedical studies.
| CAS Number | 76985-52-9 |
| Synonyms | 5-[(3aS,4S,6aR)-2-amino-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid;hydrobromide |
| Molecular Formula | C10H18BrN3O2S |
| Purity | ≥95% |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-amino-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid;hydrobromide |
| InChI | InChI=1S/C10H17N3O2S.BrH/c11-10-12-6-5-16-7(9(6)13-10)3-1-2-4-8(14)15;/h6-7,9H,1-5H2,(H,14,15)(H3,11,12,13);1H/t6-,7-,9-;/m0./s1 |
| InChIKey | JKIJLCYOCQWMQL-UFLZEWODSA-N |
| SMILES | C1C2C(C(S1)CCCCC(=O)O)N=C(N2)N.Br |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
