2-Hydroxyestradiol（Cat No.:R008171）is a catechol estrogen metabolite of estradiol formed through hydroxylation at the C-2 position. It plays a key role in estrogen metabolism and exhibits both estrogenic and antiestrogenic effects depending on the target tissue. It binds weakly to estrogen receptors but may influence cell proliferation, oxidative stress, and hormone-responsive pathways. Research suggests potential roles in carcinogenesis and cardiovascular regulation. As an endogenous compound, it is also being studied for its involvement in neuroprotection and endocrine functions, making it a valuable tool in hormone and cancer research.