2-hydroxy-5-(trifluoromethyl)benzoic Acid

• CAT Number: L040499
• CAS Number: 79427-88-6
• Molecular Formula: C8H5F3O3
• Molecular Weight: 206.12
• Purity: ≥95%
• IUPAC Name: 2-hydroxy-5-(trifluoromethyl)benzoic acid
• InChI: InChI=1S/C8H5F3O3/c9-8(10,11)4-1-2-6(12)5(3-4)7(13)14/h1-3,12H,(H,13,14)
• InChIKey: YQDOJQUHDQGQPH-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C=C1C(F)(F)F)C(=O)O)O

2-Hydroxy-5-(trifluoromethyl)benzoic acid(CAT: L040499) is a fluorinated salicylic acid derivative featuring a hydroxyl group ortho to a carboxylic acid and a trifluoromethyl substituent at the meta position. This compound combines acidic, polar, and lipophilic properties, making it useful in medicinal chemistry as a building block for drug design, especially in anti-inflammatory and antimicrobial research. The trifluoromethyl group enhances metabolic stability and bioavailability, while the hydroxyl and carboxyl functionalities support further derivatization through esterification or amidation.