2-Hydroxy-5-methyl-γ-phenylbenzenepropanol(Tolterodine Impurity)

• CAT Number: R050721
• CAS Number: 851789-43-0
• Molecular Formula: C16H18O2
• Molecular Weight: 242.32
• Purity: ≥95%
• Synonyms: 2-(3-Hydroxy-1-phenylpropyl)-4-methylphenol; 3-(2-Hydroxy-5-methylphenyl)-?3-phenylpropanol
• Storage: 4°C
• IUPAC Name: 2-(3-hydroxy-1-phenylpropyl)-4-methylphenol
• InChI: InChI=1S/C16H18O2/c1-12-7-8-16(18)15(11-12)14(9-10-17)13-5-3-2-4-6-13/h2-8,11,14,17-18H,9-10H2,1H3
• InChIKey: MJPIYYRDVSLOME-UHFFFAOYSA-N
• SMILES: CC1=CC(=C(C=C1)O)C(CCO)C2=CC=CC=C2

2-Hydroxy-5-methyl-γ-phenylbenzenepropanol（Cat No.:R050721）is a structural impurity related to tolterodine, a muscarinic receptor antagonist used in treating overactive bladder. This compound contains a phenyl-substituted propanol backbone with a hydroxyl group at the 2-position and a methyl group at the 5-position of the aromatic ring, contributing to its steric and electronic properties. As a process-related impurity, it may arise during synthesis or degradation of tolterodine. Monitoring and controlling its presence is crucial in pharmaceutical manufacturing to ensure drug purity, safety, and compliance with regulatory standards for impurity profiling and toxicological evaluation.