2-Hydroxy-3-nitro-5-(trifluoromethyl)pyridine

For research use only. Not for therapeutic Use.

  • CAT Number: L040128
  • CAS Number: 33252-64-1
  • Molecular Formula: C6H3F3N2O3
  • Molecular Weight: 208.09
  • Purity: ≥95%
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2-Hydroxy-3-nitro-5-(trifluoromethyl)pyridine(Cat No.:L040128)is a fluorinated heteroaromatic compound featuring a pyridine ring substituted with hydroxy, nitro, and trifluoromethyl groups. Its electron-deficient aromatic core, enhanced by the nitro and trifluoromethyl substituents, makes it a valuable intermediate in medicinal and agrochemical research. The hydroxy group offers a reactive handle for further functionalization, while the trifluoromethyl group improves metabolic stability and bioavailability in target molecules. This compound is often used in the design of biologically active heterocycles and as a precursor in the synthesis of complex, fluorinated pharmaceutical candidates.


CAS Number 33252-64-1
Molecular Formula C6H3F3N2O3
Purity ≥95%
IUPAC Name 3-nitro-5-(trifluoromethyl)-1H-pyridin-2-one
InChI InChI=1S/C6H3F3N2O3/c7-6(8,9)3-1-4(11(13)14)5(12)10-2-3/h1-2H,(H,10,12)
InChIKey JYXKHKBZLLIWEV-UHFFFAOYSA-N
SMILES C1=C(C(=O)NC=C1C(F)(F)F)[N+](=O)[O-]
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