2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl

• CAT Number: L041910
• CAS Number: 213697-53-1
• Molecular Formula: C26H36NP
• Molecular Weight: 393.50
• Purity: ≥95%
• IUPAC Name: 2-(2-dicyclohexylphosphanylphenyl)-N,N-dimethylaniline
• InChI: InChI=1S/C26H36NP/c1-27(2)25-19-11-9-17-23(25)24-18-10-12-20-26(24)28(21-13-5-3-6-14-21)22-15-7-4-8-16-22/h9-12,17-22H,3-8,13-16H2,1-2H3
• InChIKey: ZEMZPXWZVTUONV-UHFFFAOYSA-N
• SMILES: CN(C)C1=CC=CC=C1C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4

2-Dicyclohexylphosphino-2′-(N,N-dimethylamino)biphenyl（Cat No.:L041910）is a bulky, electron-rich biaryl phosphine ligand widely used in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig aminations. Its unique structure combines a sterically hindered dicyclohexylphosphino group with a dimethylamino-substituted biphenyl backbone, enhancing both reactivity and selectivity in metal complex formation. This ligand facilitates efficient bond formation under mild conditions, making it valuable in complex molecule synthesis, including pharmaceuticals and fine chemicals. Its ability to stabilize low-coordinate palladium centers is crucial for high catalytic activity and turnover numbers in modern organometallic chemistry.