2-Deoxy-D-glucose 6-phosphate disodium

• CAT Number: I044408
• CAS Number: 33068-19-8
• Molecular Formula: C6H11Na2O8P
• Molecular Weight: 288.10
• Purity: ≥95%
• Synonyms: disodium;[(2R,3S,4R)-2,3,4-trihydroxy-6-oxohexyl] phosphate
• InChI: InChI=1S/C6H13O8P.Na/c7-2-1-4(8)6(10)5(9)3-14-15(11,12)13;/h2,4-6,8-10H,1,3H2,(H2,11,12,13);/t4-,5-,6+;/m1./s1
• InChIKey: IZNJIWLEAMRBEY-JMWSHJPJSA-N
• SMILES: C(C=O)[C@H]([C@@H]([C@@H](COP(=O)(O)O)O)O)O.[Na]

2-Deoxy-D-glucose 6-phosphate disodium（Cat No.:I044408）is a synthetic glucose analog phosphorylated at the 6-position, commonly used to investigate glycolysis and cellular energy metabolism. As a metabolic inhibitor, it mimics glucose but cannot undergo further glycolytic processing after phosphorylation, leading to the accumulation of non-metabolizable intermediates. This disrupts ATP production and biosynthetic pathways, making it a valuable tool in cancer metabolism research. The disodium salt form enhances solubility and cellular uptake. It is frequently used in studies on tumor growth, hypoxia response, and metabolic reprogramming in cancer and neurodegenerative diseases.