2-Chloropyrimidine-5-boronic acid

• CAT Number: L015429
• CAS Number: 1003845-06-4
• Molecular Formula: C4H4BClN2O2
• Molecular Weight: 158.35
• Purity: ≥95%
• IUPAC Name: (2-chloropyrimidin-5-yl)boronic acid
• InChI: InChI=1S/C4H4BClN2O2/c6-4-7-1-3(2-8-4)5(9)10/h1-2,9-10H
• InChIKey: YTCIHPTZKKWKKC-UHFFFAOYSA-N
• SMILES: B(C1=CN=C(N=C1)Cl)(O)O

2-Chloropyrimidine-5-boronic acid（Cat No.:L015429）is a heteroaromatic boronic acid featuring a pyrimidine ring substituted with a chlorine atom at the 2-position and a boronic acid group at the 5-position. This compound is widely used in Suzuki–Miyaura cross-coupling reactions for forming carbon–carbon bonds, particularly in the synthesis of pharmaceutical and agrochemical compounds. The electron-deficient pyrimidine ring enhances its reactivity with aryl and vinyl halides, enabling the construction of complex heterocyclic frameworks. Its boronic acid functionality provides versatility in modular synthesis, making it valuable in medicinal chemistry and materials science research.