2-Chloro-N-(methylsulfonyl)acetamide

• CAT Number: L010999
• CAS Number: 202658-88-6
• Molecular Formula: C3H6ClNO3S
• Molecular Weight: 171.61
• Purity: ≥95%
• IUPAC Name: 2-chloro-N-methylsulfonylacetamide
• InChI: InChI=1S/C3H6ClNO3S/c1-9(7,8)5-3(6)2-4/h2H2,1H3,(H,5,6)
• InChIKey: BKLFBPWLPOUGTM-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)NC(=O)CCl

2-Chloro-N-(methylsulfonyl)acetamide(CAT: L010999) is a chlorinated acetamide derivative featuring a methylsulfonyl group attached to the nitrogen atom. The combination of an electrophilic α-chloroacetamide moiety and a strongly electron-withdrawing sulfonyl substituent imparts high reactivity, making it a valuable intermediate in organic synthesis. It is often used in the preparation of pharmaceuticals, agrochemicals, and bioactive heterocycles, where the chloro group serves as a site for nucleophilic substitution and the sulfonyl group modulates physicochemical properties. Its reactivity requires careful handling, as α-haloacetamides can be alkylating agents, necessitating appropriate safety precautions in laboratory and industrial applications.