2-Chloro-N-[(3-iodophenyl)methyl]-2',3'-O-(1-methylethylidene) Adenosine

• CAT Number: L018582
• CAS Number: 1000980-71-1
• Molecular Formula: C20H21ClIN5O4
• Molecular Weight: 557.80
• Purity: ≥95%
• IUPAC Name: [(3aR,4R,6R,6aR)-4-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol
• InChI: InChI=1S/C20H21ClIN5O4/c1-20(2)30-14-12(8-28)29-18(15(14)31-20)27-9-24-13-16(25-19(21)26-17(13)27)23-7-10-4-3-5-11(22)6-10/h3-6,9,12,14-15,18,28H,7-8H2,1-2H3,(H,23,25,26)/t12-,14-,15-,18-/m1/s1
• InChIKey: WCKHUABYZBGHID-SCFUHWHPSA-N
• SMILES: CC1(O[C@@H]2[C@H](O[C@H]([C@@H]2O1)N3C=NC4=C(N=C(N=C43)Cl)NCC5=CC(=CC=C5)I)CO)C

2-Chloro-N-[(3-iodophenyl)methyl]-2′,3′-O-(1-methylethylidene)adenosine（Cat No.:L018582）is a modified adenosine derivative featuring a chlorine atom at the 2-position of the purine ring, an isopropylidene (acetal) protecting group on the 2′- and 3′-hydroxyl groups of the ribose, and an N-linked 3-iodobenzyl substituent. This compound is used in nucleoside chemistry and biochemical research, particularly in studying adenosine receptor ligands and analogs. The iodophenyl moiety enables radiolabeling or cross-coupling reactions, while the isopropylidene group improves stability during synthesis. Its structure makes it valuable for probing nucleotide-protein interactions and designing biologically active nucleoside analogs.