2-Chloro-5-(trifluoromethyl)pyridine

• CAT Number: L015449
• CAS Number: 52334-81-3
• Molecular Formula: C6H3ClF3N
• Molecular Weight: 181.54
• Purity: ≥95%
• IUPAC Name: 2-chloro-5-(trifluoromethyl)pyridine
• InChI: InChI=1S/C6H3ClF3N/c7-5-2-1-4(3-11-5)6(8,9)10/h1-3H
• InChIKey: JFZJMSDDOOAOIV-UHFFFAOYSA-N
• SMILES: C1=CC(=NC=C1C(F)(F)F)Cl

2-Chloro-5-(trifluoromethyl)pyridine（Cat No.:L015449）is a halogenated heteroaromatic compound with the molecular formula C6H3ClF3N. It consists of a pyridine ring substituted with a chlorine atom at the 2-position and a trifluoromethyl group (–CF₃) at the 5-position. This compound is valuable in pharmaceutical, agrochemical, and materials chemistry as a building block for synthesizing biologically active molecules. The electron-withdrawing effects of the –Cl and –CF₃ groups influence the ring’s reactivity, making it suitable for selective functionalization through cross-coupling and nucleophilic substitution. It is typically a colorless to pale yellow liquid and should be handled with appropriate safety precautions.